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Exclusive: WHO-backed vaccine hub for Africa to copy Moderna COVID-19 shot

By Wendell Roelf CAPE TOWN (Reuters) - Efforts to develop an African base for COVID-19 vaccine production will focus on trying to replicate Moderna (NASDAQ:MRNA)'s shot, but a...
Exclusive: WHO-backed vaccine hub for Africa to copy Moderna COVID-19 shot © Reuters. FILE PHOTO: Vials of coronavirus disease (COVID-19) vaccines of Pfizer-BioNTech and Moderna are seen in the town of Ricany near Prague, Czech Republic, February 25, 2021. REUTERS/David W Cerny/File Photo

By Wendell Roelf

CAPE TOWN (Reuters) - Efforts to develop an African base for COVID-19 vaccine production will focus on trying to replicate Moderna (NASDAQ:MRNA)'s shot, but a lack of progress in talks with the U.S. company mean the project will take time, a senior WHO official told Reuters.

The drive to produce vaccines in Africa is designed to help more developing countries access COVID-19 shots after rich nations bought up most of this year's supply.

Moderna said last October it would not enforce patents related to its shot during the pandemic, raising hopes that other companies might be able to copy it and help boost COVID-19 vaccine production.

In practice, though, it is hard to replicate a vaccine without the information on how it is made, and the World Health Organization-backed tech transfer hub in South Africa - set up in June to give poorer nations the know-how to produce COVID-19 vaccines - has so far not reached a deal with the company.

"The talks have not yielded any results," Martin Friede, WHO Initiative for Vaccine Research coodinator, told Reuters.

Moderna did not respond to a request for comment.

The case highlights the challenges faced by the WHO as it battles to expand vaccine production to help address the glaring inequalities between rich and poor nations in the pandemic.

More than three quarters of the 5.5 billion COVID-19 shots administered worldwide have gone to high and upper-middle income countries, which make up just over a third of the world's population.

Currently only 3% of Africa is vaccinated, the African Union's top health official said last week, compared with more than half of the United States and three quarters of Spain.

Friede said Moderna's vaccine had been chosen as an abundance of public information and its pledge not to enforce patents made the shot slightly easier to copy than some rivals.

"We have to make a choice now. The deadline is upon us; time to start ordering chemicals. We've chosen Moderna," he said.

But even if the hub manages without Moderna's help, it could take more than a year to get a distributable vaccine as clinical trials would only begin in the latter half of 2022, he added.

TUSSLE OVER WAIVERS

In May, the United States said it would support waiving intellectual property rights for COVID-19 vaccines in order to help speed an end to the pandemic.

But the idea has faced opposition from pharmaceutical firms, which argue they need to oversee any technology transfer due to the complexity of the manufacturing process.

Pfizer (NYSE:PFE) and its partner BioNTech separately struck a deal in July for South Africa's Biovac to help make around 100 million doses a year of their COVID-19 vaccine for Africa. Their shot, like Moderna's, uses so-called mRNA technology.

However, the deal is to "fill and finish" the vaccine, the final stages of production where the product is put into vials, sealed and packaged for shipping. It does not cover the complicated process of mRNA production, which Pfizer and BioNTech will do at their European plants.

Neither responded to requests for comment.

The WHO has been trying to persuade Moderna and Pfizer-BioNTech to join forces with its African tech transfer hub.

But COVID-19 vaccine makers have warned that non-authorised producers would compete for vital raw materials and production gear that the established players - most of which have earned huge profits from vaccination - rely on.

Hub consortium partner Afrigen Biologics will produce the initial batch of doses, before transferring the skills and technology to local manufacturing partner, Biovac Institute - both are Cape Town-based - which will mass produce the vaccines.

"This is not something that we are asking industry to give us for free," Friede said about talks with the companies for access to information, adding that royalties, territorial limitations and other constraints could be built into a deal.

Healthcare analysts doubt the plan can be mobilised quickly.

"There are many steps which will require lots of iterations before they can be ready for prime time commercial grade production," said Prashant Yadav, a global healthcare supply chain expert at the Center for Global Development in Washington.

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28-09-2021 04:58:50 (UTC+7)

EUR/USD

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 EUR/USD1.1698↑ Buy
 GBP/USD1.3704Neutral
 USD/JPY110.99Neutral
 AUD/USD0.7286↑ Sell
 USD/CAD1.2625Sell
 EUR/JPY129.83↑ Buy
 EUR/CHF1.0833Neutral
 Gold1,749.80↑ Sell
 Silver22.635Neutral
 Copper4.2782↑ Sell
 Crude Oil WTI75.41↑ Sell
 Brent Oil78.62↑ Buy
 Natural Gas5.860↑ Buy
 US Coffee C194.98↑ Buy
 Euro Stoxx 504,165.48↑ Sell
 S&P 5004,443.11↑ Sell
 DAX15,573.88↑ Sell
 FTSE 1007,063.40↑ Sell
 Hang Seng24,208.78↑ Buy
 Small Cap 20002,281.79↑ Sell
 IBEX 359,002.90Buy
 BASF64.740↑ Sell
 Bayer47.47↑ Buy
 Allianz196.19↑ Buy
 Adidas278.80↑ Sell
 Lufthansa6.561↑ Buy
 Siemens AG147.27↑ Sell
 Deutsche Bank AG11.120↑ Buy
Mua/Bán 1 chỉ SJC
# So hôm qua # Chênh TG
SJC Eximbank5,665/ 5,715
(0/ 0) # 900
SJC HCM5,635/ 5,700
(0/ 0) # 885
SJC Hanoi5,635/ 5,702
(0/ 0) # 887
SJC Danang5,635/ 5,702
(0/ 0) # 887
SJC Nhatrang5,635/ 5,702
(0/ 0) # 887
SJC Cantho5,635/ 5,702
(0/ 0) # 887
Cập nhật 28-09-2021 04:58:52
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ↀ Giá vàng thế giới
$1,750.17+0.670.04%
Live 24 hour Gold Chart
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Sản phẩmVùng 1Vùng 2
RON 95-IV2204022480
RON 95-II,III2194022370
E5 RON 92-II2071021120
DO 0.05S1658016910
DO 0,001S-V1693017260
Dầu hỏa1564015950
ↂ Giá dầu thô thế giới
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$ Tỷ giá Vietcombank
Ngoại tệMua vàoBán ra
USD22.630,0022.860,00
EUR25.993,7727.346,60
GBP30.324,2231.591,18
JPY200,45212,05
KRW16,7520,39
Cập nhật lúc 18:54:42 27/09/2021
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