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AstraZeneca, Ionis eye U.S. approval after positive trial data

LONDON (Reuters) -An interim analysis of AstraZeneca (NASDAQ:AZN) and partner Ionis Pharmaceuticals (NASDAQ:IONS)' eplontersen showed the experimental drug met the main goals in a...
AstraZeneca, Ionis eye U.S. approval after positive trial data © Reuters. FILE PHOTO: The logo for AstraZeneca is seen outside its North America headquarters in Wilmington, Delaware, U.S., March 22, 2021. REUTERS/Rachel Wisniewski/File Photo

LONDON (Reuters) -An interim analysis of AstraZeneca (NASDAQ:AZN) and partner Ionis Pharmaceuticals (NASDAQ:IONS)' eplontersen showed the experimental drug met the main goals in a late-stage trial in patients with a rare, fatal disease, the Anglo-Swedish drugmaker said on Tuesday.

Based on the results, the companies plan to file an application to market the therapy in the United States later this year in patients with hereditary transthyretin-mediated amyloid polyneuropathy (ATTRv-PN).

The disease - which affects an estimated 40,000 patients globally - leads to peripheral nerve damage with motor disability within five years of diagnosis and, without treatment, is generally fatal within a decade, according to AstraZeneca.

The Cambridge, UK-based company agreed to pay California-based Ionis $200 million upfront, with up to $485 million in conditional payments following regulatory approvals as well as up to $2.9 billion in sales-related milestone payments in a deal to jointly develop and commercialise the drug last year.

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30-06-2022 23:46:18 (UTC+7)

EUR/USD

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 EUR/USD1.0476Sell
 GBP/USD1.2170↑ Sell
 USD/JPY135.74↑ Buy
 AUD/USD0.6912Sell
 USD/CAD1.2879Buy
 EUR/JPY142.18↑ Buy
 EUR/CHF0.9993↑ Sell
 Gold1,810.25↑ Sell
 Silver20.363Neutral
 Copper3.7092↑ Sell
 Crude Oil WTI107.53↑ Buy
 Brent Oil110.67↑ Buy
 Natural Gas5.671↑ Sell
 US Coffee C230.58↑ Buy
 Euro Stoxx 503,454.86↑ Buy
 S&P 5003,811.10Buy
 DAX12,783.77Neutral
 FTSE 1007,169.28Sell
 Hang Seng21,859.79Sell
 Small Cap 20001,717.50Neutral
 IBEX 358,098.70Sell
 BASF41.525↑ Buy
 Bayer56.72Neutral
 Allianz182.12Sell
 Adidas168.76Buy
 Lufthansa5.564↑ Buy
 Siemens AG97.09↑ Sell
 Deutsche Bank AG8.318Neutral
Mua/Bán 1 chỉ SJC
# So hôm qua # Chênh TG
SJC Eximbank6,810/ 6,870
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SJC HCM6,830/ 6,890
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SJC Hanoi6,830/ 6,892
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SJC Danang6,830/ 6,892
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SJC Nhatrang6,830/ 6,892
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Cập nhật 30-06-2022 23:46:20
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Cập nhật lúc 18:51:16 30/06/2022
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